Zimmermann, C. (2024). Schnelles und effizientes Genom-Editieren in Aureobasidium. BIOspektrum, 30(2), 227–229. https://doi.org/10.1007/s12268-024-2131-z
The fungus Aureobasidium pullulans is used in the industry to produce pullulan and polymalate and possesses some outstanding properties such as polyextremotolerance and an unusual life cycle. This makes A. pullulans an interesting study object, for which we need an efficient genome editing method. This article describes how CRISPR/Cas can be used for this purpose. In particular, the usage of in vitro assembled ribonucleoproteins proved to be a fast and efficient method for genome editing.
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Project title:
Ein muli-omics Ansatz zur Untersuchung des regulatorischen Netzwerks von morphologischer Plastizität in Aureobasidium pullulans: P 35642-B (FWF - Österr. Wissenschaftsfonds)
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Research Areas:
Biological and Bioactive Materials: 50% Sustainable Production and Technologies: 50%
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