This work describes processes of peripheralization and centralization in Styrian city regions. It aims at analyzing intraand interregional spatial dynamics from a process-orientated centre-periphery perspective. Specifically, demographic (outvs. in-migration), economic (disconnection vs. integration) and political dimensions (dependence vs. control) are integrated. Conceptually, these dimensions and processes are linked with current trends of suburbanization and reurbanization in the urban areas of Styria, especially in the city region of Graz. In addition, potential implications of regional development policies and spatial (urban) planning within the city region of Weststeiermark-Voitsberg are discussed. As a theoretical basis, “classical” approaches of regional economics (theory of polarized development and central place theory) are used. Besides that the macro-trends of “socio-demographic change” and the economic change towards what is called the “knowledge economy” are discussed. Methodologically, a quantitative spatial analysis is applied, combined with a qualitative research approach using verbal data obtained by expert interviews with regional actors. As main results the data show interregionally divergent trajectories of urban development in Styria. Thus a distinction between “centralized” and “peripheral” city regions can be made. Intraregionally, processes of suburbanization und reurbanization were identified to exist parallel. Regarding regional development and regional planning in Styrian city regions, the new “Steiermärkisches Landesund Regionalentwicklungsgesetz 2018” provides an important legal framework. In addition, the IWB/EFRE program (2014-2020) provides the financial means for the funding of projects, particularly in relation to intercommunal cooperation and the development of industrial locations.