This master's thesis entails a description of a web application with a dynamic central database which allows the creation and management of clinical studies. Over a multi user system, users are able to individually create their own multi-centered clinical studies as well as combine different clinical studies for statistical analysis. With the latest technology (Ajax and JSF) it is possible to create data entry screens quickly, easily and without any programming. The unique graphical user interface, allows dragging and dropping elements for a high-speed design of electronic case report forms (eCRF). Through the dynamical structure of the database, there are no limitations to the creation of individual clinical studies. These fields can easily be created and managed by the different users. In order to facilitate a clearly laid-out clinical study, the user has the ability to create and integrate categories. The fields can then be associated with the category which provides a clear overview of the clinical study. By combining the studies in a single web application, the users are able to compare in greater depth the different values from different treatments. In particular, the time and effort required to capture the data should be reduced and duplicate steps, such as duplicate patient information, should be avoided. As a result, the clinical study documentation system, AlphaNet, is in a league of its own.